The Liver Health Formula: A Buyer’s Guide

The Liver Health Formula: A Buyer’s Guide

There isn’t enough evidence to support the claims that supplements like milk thistle, artichoke leaf, dandelion root, or even products like liver renew, can help detox or treat the liver. It is preferable to make healthy lifestyle decisions in order to enhance your health.

Do liver supplements work?

The effectiveness of liver supplements including liver renew, is a topic of debate and scientific research. While some liver cleanse supplements claim to support liver health and function, it is important to note that the evidence supporting their effectiveness is limited. 

Advertisements for best liver repair supplement may state that these goods achieve the following:

  • detoxify the liver and kidneys
  • support respiratory and immune system function
  • increase metabolism and promote weight loss
  • treat liver ailments
  • promote overall liver health
  • optimize liver function
  • promote the production of bile
  • protect liver cells from inflammation and allergic reactions

The liver is a vital organ responsible for various metabolic processes and detoxification. However, there is currently insufficient scientific evidence to conclude that taking liver supplements can significantly improve liver health or prevent liver diseases. 

The best way to support liver health is to maintain a balanced and healthy lifestyle, including a nutritious diet, regular physical activity, limited alcohol consumption, and avoiding exposure to toxins. If you have concerns about your liver health, it is advisable to consult with a healthcare professional who can provide personalized guidance and recommend appropriate diagnostic tests or treatments based on your specific situation.

Popular Liver Support Supplement Ingredients

Some popular ingredients found in healthy liver supplements include: 

Milk Thistle

Milk thistle (Silybum marianum) is a commonly used herb believed to have liver-protective properties. It contains a compound called silymarin, which is thought to promote liver cell regeneration and protect against toxins. 

According to studies, silymarin may assist people with non-alcoholic fatty liver disease (NAFLD). The study revealed that silymarin may improve liver enzymes in people with NAFLD, but the quality of evidence was moderate, and more rigorous trials are needed to demonstrate its long-term benefits.

Artichoke Extract

Artichoke extract is derived from the leaves of the artichoke plant (Cynara scolymus) and is believed to support liver function and aid in digestion. 

Dandelion Root

Dandelion root (Taraxacum officinale) is often included in liver supplements due to its historical use in traditional medicine to support liver health and promote detoxification. 

N-acetyl cysteine (NAC)

NAC is an antioxidant and a precursor to glutathione, a substance involved in liver detoxification processes. It is sometimes included in liver supplements for its potential ability to support liver function. 

A 2014 research investigated the use of NAC in people with acetaminophen overdose. The study discovered that NAC administration enhanced liver function parameters in comparison to a placebo. However, further study is needed to evaluate its efficacy in promoting overall liver health.

Alpha-lipoic acid

Alpha-lipoic acid (ALA) is an antioxidant that may help protect liver cells from oxidative damage and support liver health. 

  • Vitamin A
  • Vitamin C
  • Vitamin E
  • Selenium
  • Zinc

These vitamins and minerals play essential roles in supporting overall health and may contribute to liver health by reducing oxidative stress and supporting liver enzymes.

Other ingredients

Besides milk thistle, artichoke, and dandelion, liver detox supplements set themselves apart with the addition of a combination of additional ingredients. This can involve items such as:

  • wild tam Mexican root
  • yellow dock root extract
  • Hawthorn berry
  • chance piedra

It is important to note that while these ingredients are often found in liver support supplements, their efficacy in supporting liver health has not been definitively proven through extensive scientific research. As with any dietary supplement, it is advisable to consult with a healthcare professional before starting any new supplement regimen.


Liver health formulas can be purchased from various sources. Here are some common places where you can find liver health supplements: 


Local pharmacies or drugstores often carry a range of dietary supplements, including liver health formulas. You can visit the supplement section and inquire about liver health supplements. 

Health food stores

Many health food stores specialize in natural and organic products, including supplements for liver health. These stores often have a wide selection of liver health formulas. 

Online retailers

Numerous online retailers sell dietary liver detox supplements, providing a convenient way to browse and purchase liver health formulas. Some popular online platforms include Amazon, Vitacost, iHerb, and Thrive Market. Ensure you choose reputable sellers and read product reviews before making a purchase. 

Specialty supplement stores

Some stores specialize in selling dietary supplements and may have a broader selection of liver health formulas compared to general retailers. 

These stores often have knowledgeable staff who can assist you in finding the right product. Remember, it is important to carefully research the brand, read product labels, and consult with a healthcare professional before starting any new supplement regimen.

Is It Safe To Use Liver Supplements?

When used as indicated and in suitable amounts, liver health supplements can be considered safe. However, it is critical to select high-quality supplements from recognized manufacturers and check with a healthcare practitioner before beginning any new supplementing routine, particularly if you have underlying medical concerns or are taking drugs.

Certain healthy liver supplements may interfere with medicines or aggravate pre-existing health conditions, so consult a certified healthcare expert about your specific health requirements and concerns.

Protecting Your Liver Naturally

While liver health formulas may provide some relief, a comprehensive approach to liver health is essential. Here are some important lifestyle changes that might improve your liver and provide overall health benefits:

Maintain a Healthy Weight: Losing weight, even a small amount, can improve liver function in people with NAFLD.
Adopt a Balanced Diet: Eat fruits, vegetables, and whole grains, while reducing processed foods, added sweets, and harmful fats.
Moderate Alcohol Drinking: Excess alcohol drinking is a major cause of liver damage. Aim for moderate alcohol use or consider abstaining completely.
Exercise: Regular physical exercise can enhance overall health and may boost liver function.
Manage Stress: Chronic stress can harm liver health. Yoga, meditation, and deep breathing exercises are all effective stress-management techniques.
Get Vaccinated: Vaccines, such as hepatitis A and B, can protect your liver from these infections.

If you enjoyed this article, you may also want to read this article on The Best Foods to Detox and Protect Your Liver.

*This information is not intended to serve as a substitute for professional medical or dietary advice tailored to individual needs.

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Dr. Kimberly Langdon

Kimberly Langdon

Dr. Kimberly Langdon has been an MD for 31 years, board-certified obstetrician/gynecologist with 19-years of clinical experience. She graduated from The Ohio State University College of Medicine, earning Honors in many rotations. She then completed her OB/GYN residency program at The Ohio State University Medical Center, earning first-place accolades for her Senior Research Project and Score of 98th percentile on a National Proficiency Test.

During her clinical career, she delivered over 2000 babies and specialized in minimally invasive procedures, menopause, endometriosis, menstrual disorders, and polycystic ovarian syndrome. After retiring from clinical practice, she founded a medical device company to commercialize her two patented and four patent-pending medical devices for both life-threatening and non-life-threatening infections.

Kimberly Langdon M.D.

Founder and Chief Scientific Officer, Coologics, 2010-present
The Ohio State University College of Medicine, Doctor of Medicine 1987-1991
The Ohio State University Hospital Department of Obstetrics and Gynecology Residency Program 1991-1995
Private practice 1995-2010

Po-Chang Hsu

Po-Chang Hsu

Po-Chang Hsu, M.D., received his medical doctorate from Tufts University School of Medicine in Boston. During his medical school training, Dr. Hsu worked with various patients, including adult and pediatric patients with acute and chronic conditions. Dr. Hsu’s interests include neurology, psychiatry, pediatrics, and sleep medicine.

Before medical school, Dr. Hsu finished a master’s degree at Harvard University and wrote a thesis on neuroimaging in schizophrenia patients at Brigham and Women’s Hospital, a Harvard Medical School-affiliated hospital. Dr. Hsu was also a part of the 2008 NASA Phoenix Lander Mission team, which sent a robotic spacecraft to the North polar region of Mars. Dr. Hsu also had research experience on neuroimaging in neonates at Boston Children’s Hospital, another Harvard Medical School-affiliated Hospital.

Since graduating from medical school, Dr. Hsu has worked as a full-time medical writer and consultant. In addition, he has experience writing and ghostwriting books and articles for physicians and health technology start-up companies. Dr. Hsu believes good communication between healthcare providers and patients creates the best results.


-Peer Reviewed Journal Article:
Kounaves, S.P., Hecht, M.H., West, S.J., Morookian, J.-M., Young, S.M.M., Quinn, R., Grunthaner, P., Wen, X., Weilert, M., Cable, C.A., Fisher, A., Gospodinova, K., Kapit, J., Stroble, S., Hsu, P.-C., Clark, B.C., Ming, D.W. and Smith, P.H. The MECA wet chemistry laboratory on the 2007 phoenix mars scout Lander. Journal of Geophysical Research. 2009, Mar; 114(E3): 10.1029/2008je003084.

-Poster Presentation:
2011 Harvard Psychiatry Mysell Poster Session; Boston, MA
Hsu, P.C., Rathi, Y., Eckbo, R., Nestor, P., Niznikiewicz, M., Thompson, E., Kubicki, M., Shenton, M.E. (March, 2011). Two-Tensor Diffusion Tensor Imaging of Acoustic Radiations in Schizophrenia

Dr. Nicolette Natale

Nicolette Natale

Dr. Nicolette Natale is a physician, with a background in Psychology, General Medicine, and English Literature, combining her expertise to provide readers with the most accurate, easy-to-understand, and comprehensive information regarding healthcare. She received her Doctorate in Osteopathic Medicine from Nova Southeastern University, and her bachelor’s in English Literature and Psychology from the University of Miami. Dr. Natale seeks to empower individuals with knowledge, fostering a greater understanding of holistic health and encouraging a proactive approach to well-being